The laboratories of Drs. Nan Yang and Herbert Zheng Wu in the Department of Neuroscience at Icahn School of Medicine at Mount Sinai have an exciting opportunity for a Joint Postdoctoral Fellow to join our team. The successful candidate will lead independent projects to examine the circuit and computational logic in human brain organoids and their applications in modeling neuropsychiatric disorders. We are looking for a candidate who is highly motivated, critical, and inquisitive and has excellent communication skills. The candidate should have a recent Ph.D. or M.D/Ph.D. in a relevant field including neuroscience, biology, and biomedical engineering. We are interested in candidates with experience in stem cell biology, genomics, and/or systems neuroscience.

You can expect the PIs to have a sincere interest in your work and support you at every stage of your career. We will help you realize your potential, do meaningful and fun science with the team, and develop a vision as an independent scientist. You will join a vibrant neuroscience community at Mount Sinai and will have opportunities to interact with a broad network of neuroscientists in the New York City. We will provide a competitive salary as well as housing and health benefits.

The Yang Laboratory is interested in the fundamental neurobiological underpinnings that lead to psychiatric and neurological disorders, examining the root causes, mechanisms, and developmental trajectories of these afflictions. Our research is unequivocally grounded in developmental biology, utilizing human pluripotent stem cells to reconstruct and decipher the intricate processes of human brain development. Employing cutting-edge, high-throughput in vitro model systems and implementing the latest single-cell omics techniques, we aim to illuminate the intricate processes of neural tissue establishment during fetal development, the formation of neural networks, and how these processes vary among individuals, ultimately providing critical insights into psychiatric and neurological disorders.

The Wu Laboratory is interested in understanding how diverse neuronal populations (in the brain or organoids) give rise to complex behavior. To understand these questions, we will apply a variety of modern methodologies including large-scale calcium imaging, single-cell omics, in vivo electrophysiology, optogenetics, quantitative behavioral analysis, and computational modeling.

To apply, please send a cover letter, your CV, and the contact information of three referees to nan.yang1@mssm.edu and zheng.wu@mssm.edu. Thank you for your interest in joining our team.